Classifier Spot Count Optimization of Automated Fluorescent Slide Scanning System

Purpose: Ionizing radiation induced foci (IRIF) known also as DNA repair foci represent the most sensitive endpoint for assessing DNA double strand breaks (DSB). IRIF are usually visualized and enumerated with the aid of fluorescence microscopy using antibodies to γH2AX and 53BP1. Although several a...

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Bibliographic Details
Main Authors: Lucian Zastko, Martin Bereta, Jaroslav Timko, Igor Belyaev
Format: Article
Language:English
Published: Sciendo 2022-04-01
Series:Acta Medica Martiniana
Subjects:
Online Access:https://doi.org/10.2478/acm-2022-0004