Extracellular vesicles produced by avian pathogenic Escherichia coli (APEC) activate macrophage proinflammatory response and neutrophil extracellular trap (NET) formation through TLR4 signaling

Extracellular vesicles produced by avian pathogenic Escherichia coli (APEC) activate macrophage proinflammatory response and neutrophil extracellular trap (NET) formation through TLR4 signaling

Abstract Background Avian pathogenic Escherichia coli (APEC) is the major pathogen causing important avian diseases in poultry. As an important subtype of extraintestinal pathogenic E. coli, APEC has zoonotic potential and is considered a foodborne pathogen. APEC extracellular vesicles (EVs) may pla...

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Bibliographic Details
Main Authors: Zhongxing Wang, Dongyu Zhu, Yuting Zhang, Fufang Xia, Jiaying Zhu, Jianjun Dai, Xiangkai Zhuge
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Microbial Cell Factories
Subjects:
Avian pathogenic Escherichia Coli
Extracellular vesicle
TLR4 signaling
Inflammatory response
Neutrophil extracellular trap
Online Access:https://doi.org/10.1186/s12934-023-02171-6

Internet

https://doi.org/10.1186/s12934-023-02171-6

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