Definition of the immunogenic forms of modified human LDL recognized by human autoantibodies and by rabbit hyperimmune antibodies

Definition of the immunogenic forms of modified human LDL recognized by human autoantibodies and by rabbit hyperimmune antibodies

Humans and laboratory animals recognize human modified LDL as immunogenic. Immune complexes (ICs) isolated from human sera contain malondialdehyde-modified LDL (MDA-LDL) and N ε(carboxymethyl)lysine-modified LDL (CML-LDL) as well as antibodies reacting with MDA-LDL, copper-oxidized LDL (OxLDL), CML-...

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Bibliographic Details
Main Authors: Gabriel Virella, Suzanne R. Thorpe, Nathan L. Alderson, M. Brooks Derrick, Charlyne Chassereau, J. Matthew Rhett, Maria F. Lopes-Virella
Format: Article
Language:English
Published: Elsevier 2004-10-01
Series:Journal of Lipid Research
Subjects:
low density lipoprotein modifications
low density lipoprotein autoantibodies
modified low density lipoprotein antibodies
immunology of atherosclerosis
autoimmunity
atherosclerosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520312591

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http://www.sciencedirect.com/science/article/pii/S0022227520312591

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