Immunoglobulin directly enhances differentiation of oligodendrocyte-precursor cells and remyelination

Abstract Multiple sclerosis (MS) is an inflammatory demyelinating disease characterized by multiple lesions in the central nervous system. Although the role of B cells in MS pathogenesis has attracted much attention, but the detailed mechanisms remain unclear. To investigate the effects of B cells o...

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Bibliographic Details
Main Authors: Yaguang Li, Daisuke Noto, Yasunobu Hoshino, Miho Mizuno, Soichiro Yoshikawa, Sachiko Miyake
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-36532-3