Modulation of the photobehavior of gefitinib and its phenolic metabolites by human transport proteins

The photobiological damage that certain drugs or their metabolites can photosensitize in proteins is generally associated with the nature of the excited species that are generated upon interaction with UVA light. In this regard, the photoinduced damage of the anticancer drug gefitinib (GFT) and its...

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Bibliographic Details
Main Authors: Lorena Tamarit, Meryem El Ouardi, Emilio Lence, Inmaculada Andreu, Concepcion González-Bello, Miguel A. Miranda, Ignacio Vayá
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-05-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1387057/full