Silencing of Opisthorchis viverrini Tetraspanin Gene Expression Results in Reduced Secretion of Extracellular Vesicles

Silencing of Opisthorchis viverrini Tetraspanin Gene Expression Results in Reduced Secretion of Extracellular Vesicles

Inter-phylum transfer of molecular information is exquisitely exemplified in the uptake of parasite extracellular vesicles (EVs) by their target mammalian host tissues. The oriental liver fluke, Opisthorchis viverrini is the major cause of bile duct cancer in people in Southeast Asia. A major mechan...

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Bibliographic Details
Main Authors: Sujittra Chaiyadet, Javier Sotillo, Watchara Krueajampa, Sophita Thongsen, Michael Smout, Paul J. Brindley, Thewarach Laha, Alex Loukas
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Opisthorchis viverrini
liver fluke
extracellular vesicle
endocytosis
tetraspanin
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.827521/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.827521/full

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