Combined Analysis of Expression Profiles in a Mouse Model and Patients Identified BHMT2 as a New Regulator of Lipid Metabolism in Metabolic-Associated Fatty Liver Disease

Combined Analysis of Expression Profiles in a Mouse Model and Patients Identified BHMT2 as a New Regulator of Lipid Metabolism in Metabolic-Associated Fatty Liver Disease

Metabolic associated fatty liver disease (MAFLD) is associated with obesity, type 2 diabetes mellitus, and other metabolic syndromes. Farnesoid X receptor (FXR, NR1H4) plays a prominent role in hepatic lipid metabolism. This study combined the expression of liver genes in FXR knockout (KO) mice and...

Full description

Bibliographic Details
Main Authors: Yongqiang Ma, Zhi Tan, Qiang Li, Wenling Fan, Guangshun Chen, Yangyang Bin, Yi Zhou, Junfang Yi, Xiaohua Luo, Jieqiong Tan, Zhongzhou Si, Jiequn Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
FXR
metabolic associated fatty liver disease
transcription analysis
BHMT2
PPAR γ
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.741710/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.741710/full

Similar Items