EYA4 promotes breast cancer progression and metastasis through its role in replication stress avoidance

EYA4 promotes breast cancer progression and metastasis through its role in replication stress avoidance

Abstract The Eyes Absent (EYA) family of proteins is an atypical group of four dual-functioning protein phosphatases (PP), which have been linked to many vital cellular processes and organogenesis pathways. The four family members of this PP family possess transcriptional activation and phosphatase...

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Bibliographic Details
Main Authors: Bárbara de la Peña Avalos, Romain Tropée, Pascal H. G. Duijf, Eloïse Dray
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Molecular Cancer
Subjects:
EYA4
Protein phosphatase
Cell cycle
DNA replication
Breast cancer
Online Access:https://doi.org/10.1186/s12943-023-01861-4

Internet

https://doi.org/10.1186/s12943-023-01861-4

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