A Broad Antiviral Strategy: Inhibitors of Human DHODH Pave the Way for Host-Targeting Antivirals against Emerging and Re-Emerging Viruses

A Broad Antiviral Strategy: Inhibitors of Human DHODH Pave the Way for Host-Targeting Antivirals against Emerging and Re-Emerging Viruses

New strategies to rapidly develop broad-spectrum antiviral therapies are urgently required for emerging and re-emerging viruses. Host-targeting antivirals (HTAs) that target the universal host factors necessary for viral replication are the most promising approach, with broad-spectrum, foresighted f...

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Bibliographic Details
Main Authors: Yucheng Zheng, Shiliang Li, Kun Song, Jiajie Ye, Wenkang Li, Yifan Zhong, Ziyan Feng, Simeng Liang, Zeng Cai, Ke Xu
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Viruses
Subjects:
host-targeting antivirals (HTAs)
DHODH inhibitors (DHODHi)
pyrimidine synthesis
broad-spectrum antivirals
Online Access:https://www.mdpi.com/1999-4915/14/5/928

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https://www.mdpi.com/1999-4915/14/5/928

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