Synthesis and Impurity Research of 2-Thioadenosine Monohydrate

Abstract 2-Thioadenosine monohydrate (1) is a vital intermediate in the synthesis of cangrelor. However, its industrial-scale preparation process and the analysis of the impurities formed during this process remained largely unknown. Herein, cangrelor was synthesized from oxidate adenosine...

Full description

Bibliographic Details
Main Authors: Jing-Jing Xiang, Bi-Bo Jiang, Wen-Qing Sun, Fu-Li Zhang, Jun Yu
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2023-06-01
Series:Pharmaceutical Fronts
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1768692