Synthesis and Impurity Research of 2-Thioadenosine Monohydrate

Synthesis and Impurity Research of 2-Thioadenosine Monohydrate

Abstract 2-Thioadenosine monohydrate (1) is a vital intermediate in the synthesis of cangrelor. However, its industrial-scale preparation process and the analysis of the impurities formed during this process remained largely unknown. Herein, cangrelor was synthesized from oxidate adenosine...

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Bibliographic Details
Main Authors:	Jing-Jing Xiang, Bi-Bo Jiang, Wen-Qing Sun, Fu-Li Zhang, Jun Yu
Format:	Article
Language:	English
Published:	Georg Thieme Verlag KG 2023-06-01
Series:	Pharmaceutical Fronts
Subjects:	cangrelor 2-thioadenosine monohydrate a kilogram scale impurities
Online Access:	http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1768692

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