Synthesis and Inhibitory Activity of Machaeridiol-Based Novel Anti-MRSA and Anti-VRE Compounds and Their Profiling for Cancer-Related Signaling Pathways

Synthesis and Inhibitory Activity of Machaeridiol-Based Novel Anti-MRSA and Anti-VRE Compounds and Their Profiling for Cancer-Related Signaling Pathways

Three unique 5,6-<i>seco</i>-hexahydrodibenzopyrans (<i>seco</i>-HHDBP) machaeridiols A–C, reported previously from <i>Machaerium</i> Pers., have displayed potent activities against methicillin-resistant <i>Staphylococcus aureus</i> (MRSA), vancomycin-...

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Bibliographic Details
Main Authors: Mallika Kumarihamy, Siddharth Tripathi, Premalatha Balachandran, Bharathi Avula, Jianping Zhao, Mei Wang, Maria M. Bennett, Jin Zhang, Mary A. Carr, K. Michael Lovell, Ocean I. Wellington, Mary E. Marquart, N. P. Dhammika Nanayakkara, Ilias Muhammad
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Molecules
Subjects:
machaeridiol analogs
synthesis
antibacterial
MRSA
VRE
in vivo nosocomial MRSA assay
Online Access:https://www.mdpi.com/1420-3049/27/19/6604

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https://www.mdpi.com/1420-3049/27/19/6604

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