Aidi injection inhibits the migration and invasion of gefitinib-resistant lung adenocarcinoma cells by regulating the PLAT/FAK/AKT pathway

Aidi injection inhibits the migration and invasion of gefitinib-resistant lung adenocarcinoma cells by regulating the PLAT/FAK/AKT pathway

Abstract Background With extended gefitinib treatment, the therapeutic effect in some non-small cell lung cancer (NSCLC) patients declined with the development of drug resistance. Aidi injection (ADI) is utilized in various cancers as a traditional Chinese medicine prescription. This study explores...

Full description

Bibliographic Details
Main Authors: Jingyuan Zhang, Siyun Yang, Xiaodong Chen, Fanqin Zhang, Siyu Guo, Chao Wu, Tieshan Wang, Haojia Wang, Shan Lu, Chuanqi Qiao, Xiaoguang Sheng, Shuqi Liu, Xiaomeng Zhang, Hua Luo, Qinglin Li, Jiarui Wu
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Chinese Medicine
Subjects:
Non-small cell lung cancer
Aidi injection
Gefitinib resistance
PLAT/FAK/AKT pathway
Online Access:https://doi.org/10.1186/s13020-024-01054-1

Internet

https://doi.org/10.1186/s13020-024-01054-1

Similar Items