Analysis of Several Pathways for Efficient Killing of Prostate Cancer Stem Cells: A Central Role of NF-κB RELA

Analysis of Several Pathways for Efficient Killing of Prostate Cancer Stem Cells: A Central Role of NF-κB RELA

Prostate cancer is a common cause of death worldwide. Here, we isolated cancer stem cells (CSCs) from four adenocarcinomas of the prostate (Gleason scores from 3 + 3 up to 4 + 5). CSCs were characterized by the expression of the stem cell markers <i>TWIST</i>, the epithelial cell adhesio...

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Bibliographic Details
Main Authors: Kaya E. Witte, Jesco Pfitzenmaier, Jonathan Storm, Melanie Lütkemeyer, Clara Wimmer, Wiebke Schulten, Nele Czaniera, Marvin Geisler, Christine Förster, Ludwig Wilkens, Cornelius Knabbe, Fritz Mertzlufft, Barbara Kaltschmidt, Jan Schulte am Esch, Christian Kaltschmidt
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
prostate cancer
cancer stem cells
nuclear factor “kappa-light-chain-enhancer” of activated B-cells
tumor necrosis factor
interferon gamma
immune checkpoint therapy
Online Access:https://www.mdpi.com/1422-0067/22/16/8901

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https://www.mdpi.com/1422-0067/22/16/8901

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