The Biologist’s Guide to the Glucocorticoid Receptor’s Structure

The Biologist’s Guide to the Glucocorticoid Receptor’s Structure

The glucocorticoid receptor α (GRα) is a member of the nuclear receptor superfamily and functions as a glucocorticoid (GC)-responsive transcription factor. GR can halt inflammation and kill off cancer cells, thus explaining the widespread use of glucocorticoids in the clinic. However, side effects a...

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Bibliographic Details
Main Authors: Nick Deploey, Laura Van Moortel, Inez Rogatsky, Frank Peelman, Karolien De Bosscher
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Cells
Subjects:
glucocorticoid receptor
glucocorticoids
structure
nuclear receptor
N-terminal domain
DNA-binding domain
Online Access:https://www.mdpi.com/2073-4409/12/12/1636

Internet

https://www.mdpi.com/2073-4409/12/12/1636

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