Inositol pyrophosphate dynamics reveals control of the yeast phosphate starvation program through 1,5-IP8 and the SPX domain of Pho81

Inositol pyrophosphate dynamics reveals control of the yeast phosphate starvation program through 1,5-IP8 and the SPX domain of Pho81

Eukaryotic cells control inorganic phosphate to balance its role as essential macronutrient with its negative bioenergetic impact on reactions liberating phosphate. Phosphate homeostasis depends on the conserved INPHORS signaling pathway that utilizes inositol pyrophosphates and SPX receptor domains...

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Bibliographic Details
Main Authors: Valentin Chabert, Geun-Don Kim, Danye Qiu, Guizhen Liu, Lydie Michaillat Mayer, Muhammed Jamsheer K, Henning J Jessen, Andreas Mayer
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-09-01
Series:eLife
Subjects:
SPX domain
phosphate homeostasis
inositol pyrophosphate
PHO pathway
nutrient signaling
Cryptococcus neoformans
Online Access:https://elifesciences.org/articles/87956

Internet

https://elifesciences.org/articles/87956

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