Dispersibility and Storage Stability Optimization of High Dose Isoniazid Dry Powder Inhalation Formulations with <span style="font-variant: small-caps">L</span>-Leucine or Trileucine

Dispersibility and Storage Stability Optimization of High Dose Isoniazid Dry Powder Inhalation Formulations with <span style="font-variant: small-caps">L</span>-Leucine or Trileucine

Tuberculosis is the leading cause of death from a single infectious pathogen worldwide. Lately, the targeted delivery of antibiotics to the lungs via inhalation has received increasing interest. In a previous article, we reported on the development of a spray-dried dry powder isoniazid formulation c...

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Bibliographic Details
Main Authors: Imco Sibum, Paul Hagedoorn, Markus P. G. Kluitman, Martijn Kloezen, Henderik W. Frijlink, Floris Grasmeijer
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Pharmaceutics
Subjects:
high dose pulmonary delivery
dry powder inhaler
drug formulation
inhalation
tuberculosis
Online Access:https://www.mdpi.com/1999-4923/12/1/24

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https://www.mdpi.com/1999-4923/12/1/24

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