Loss of Hepatic Surf4 Depletes Lipid Droplets in the Adrenal Cortex but Does Not Impair Adrenal Hormone Production

Loss of Hepatic Surf4 Depletes Lipid Droplets in the Adrenal Cortex but Does Not Impair Adrenal Hormone Production

The adrenal gland produces steroid hormones to play essential roles in regulating various physiological processes. Our previous studies showed that knockout of hepatic Surf4 (Surf4LKO) markedly reduced fasting plasma total cholesterol levels in adult mice, including low-density lipoprotein and high-...

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Bibliographic Details
Main Authors: Xiaole Chang, Yongfang Zhao, Shucun Qin, Hao Wang, Bingxiang Wang, Lei Zhai, Boyan Liu, Hong-mei Gu, Da-wei Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
proprotein convertase subtilisin/kexin 9
LDL–cholesterol
cholesterol
triglyceride
atherosclerosis
LDL receptor (LDLR)
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.764024/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2021.764024/full

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