The Food Additive β-Caryophyllene Exerts Its Neuroprotective Effects Through the JAK2-STAT3-BACE1 Pathway

The Food Additive β-Caryophyllene Exerts Its Neuroprotective Effects Through the JAK2-STAT3-BACE1 Pathway

Despite extensive research on Alzheimer’s disease (AD), its diagnosis and treatment remain challenging, and no effective therapies are currently available. Amyloid β (Aβ) extracellular plaques and intracellular neurofibrillary tangles are the histological characteristics of AD that have been directl...

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Bibliographic Details
Main Authors: Yujia Zhang, Qiaoyan Huang, Sichen Wang, Ziqian Liao, Haichao Jin, Shuo Huang, Xiao Hong, Yiming Liu, Jie Pang, Qing Shen, Qingcheng Wang, Changyu Li, Liting Ji
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer’s disease
amyloid-β protein precursor
amyloid β
PC-12 cell
β-caryophyllene
JAK2-STAT3-BACE1
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.814432/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2022.814432/full

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