Altered brain activation in a reversal learning task unmasks adaptive changes in cognitive control in writer's cramp

Altered brain activation in a reversal learning task unmasks adaptive changes in cognitive control in writer's cramp

Previous receptor binding studies suggest dopamine function is altered in the basal ganglia circuitry in task-specific dystonia, a condition characterized by contraction of agonist and antagonist muscles while performing specific tasks. Dopamine plays a role in reward-based learning. Using fMRI, thi...

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Bibliographic Details
Main Authors: Kirsten E. Zeuner, Arne Knutzen, Oliver Granert, Simone Sablowsky, Julia Götz, Stephan Wolff, Olav Jansen, Dirk Dressler, Susanne A. Schneider, Christine Klein, Günther Deuschl, Thilo van Eimeren, Karsten Witt
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:NeuroImage: Clinical
Subjects:
Writer's cramp
Task specific dystonia
Functional magnetic resonance imaging
Reversal learning
Reward
Probabilistic response
Basal ganglia
Striatum
DRD2/ANKK1-TaqIa polymorphism
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158215300231

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http://www.sciencedirect.com/science/article/pii/S2213158215300231

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