Neutrophil breaching of the blood vessel pericyte layer during diapedesis requires mast cell-derived IL-17A

The blood vessel wall is a complex multi-layered structure, yet upon injury or infection, neutrophil leukocytes are rapidly migrating from the blood stream to the affected tissues, by a process termed diapedesis. Authors here show that the final steps of diapedesis through the outer pericyte layer i...

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Bibliographic Details
Main Authors: Régis Joulia, Idaira María Guerrero-Fonseca, Tamara Girbl, Jonathon A. Coates, Monja Stein, Laura Vázquez-Martínez, Eleanor Lynam, James Whiteford, Michael Schnoor, David Voehringer, Axel Roers, Sussan Nourshargh, Mathieu-Benoit Voisin
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34695-7