The changes of Treg and Th17 cells relate to serum 25(OH)D in patients with initial-onset childhood systemic lupus erythematosus

The changes of Treg and Th17 cells relate to serum 25(OH)D in patients with initial-onset childhood systemic lupus erythematosus

BackgroundT helper 17 (Th17) cells and regulatory T cells (Treg) are known to play a crucial role in the pathogenesis of systemic lupus erythematosus (SLE). Improving the balance between Treg and Th17 cells can be a promising new therapeutic target in SLE patients. Vitamin D has a significant impact...

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Bibliographic Details
Main Authors: Li-jun Jiang, Zan-hua Rong, Hui-feng Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Pediatrics
Subjects:
25(OH)D
SLE
Treg
Th17
cytokines
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2023.1228112/full

Internet

https://www.frontiersin.org/articles/10.3389/fped.2023.1228112/full

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