<i>N</i>-Acetyl-Cysteine Regenerates Albumin Cys34 by a Thiol-Disulfide Breaking Mechanism: An Explanation of Its Extracellular Antioxidant Activity

<i>N</i>-Acetyl-Cysteine Regenerates Albumin Cys34 by a Thiol-Disulfide Breaking Mechanism: An Explanation of Its Extracellular Antioxidant Activity

In the present paper, the extracellular antioxidant activity of <i>N</i>-acetyl-cysteine (NAC) is explained by considering its ability to regenerate the free form of albumin Cys34 by breaking the disulfide bond of the cysteinylated form (HSA-Cys). NAC’s capability to regenerate albumin C...

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Bibliographic Details
Main Authors: Alessandra Altomare, Giovanna Baron, Maura Brioschi, Martina Longoni, Riccardo Butti, Edoardo Valvassori, Elena Tremoli, Marina Carini, Piergiuseppe Agostoni, Giulio Vistoli, Cristina Banfi, Giancarlo Aldini
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Antioxidants
Subjects:
<i>N</i>-acetyl-cysteine
albumin
Cys34
cysteine
antioxidant
plasma
Online Access:https://www.mdpi.com/2076-3921/9/5/367

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https://www.mdpi.com/2076-3921/9/5/367

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