Exploring Antibiotic-Potentiating Effects of Tobramycin–Deferiprone Conjugates in <i>Pseudomonas aeruginosa</i>

Metal ions, including Fe<sup>3+</sup>, affect the target site binding of some antibiotics and control the porin- and siderophore-mediated uptake of antibiotics. Amphiphilic tobramycins are an emerging class of antibiotic potentiators capable of synergizing with multiple classes of antibi...

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Bibliographic Details
Main Authors: Karan Gandhi, Shiv Dhiman, Rajat Arora, Danzel Marie Ramirez, Danyel Ramirez, Gilbert Arthur, Frank Schweizer
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/12/8/1261