Enhanced Levels of Peroxisome-Derived H<sub>2</sub>O<sub>2</sub> Do Not Induce Pexophagy but Impair Autophagic Flux in HEK-293 and HeLa Cells
Peroxisomes are functionally specialized organelles that harbor multiple hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>)-producing and -degrading enzymes. Given that this oxidant functions as a major redox signaling agent, peroxisomes have the intrinsic ability to mediate and...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-03-01
|
Series: | Antioxidants |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-3921/12/3/613 |