Discrete Correlation Summation Clustering Reveals Differential Regulation of Liver Metabolism by Thrombospondin-1 in Low-Fat and High-Fat Diet-Fed Mice

Discrete Correlation Summation Clustering Reveals Differential Regulation of Liver Metabolism by Thrombospondin-1 in Low-Fat and High-Fat Diet-Fed Mice

Thrombospondin-1 (TSP1) is a matricellular protein with many important roles in mediating carcinogenesis, fibrosis, leukocyte recruitment, and metabolism. We have previously shown a role of diet in the absence of TSP1 in liver metabolism in the context of a colorectal cancer model. However, the meta...

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Bibliographic Details
Main Authors: Steven M. Bronson, Brian Westwood, Katherine L. Cook, Nancy J. Emenaker, Mark C. Chappell, David D. Roberts, David R. Soto-Pantoja
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Metabolites
Subjects:
discrete correlation summation
thrombospondin
diet
non-alcoholic fatty liver disease
liver
oxidative stress
Online Access:https://www.mdpi.com/2218-1989/12/11/1036

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https://www.mdpi.com/2218-1989/12/11/1036

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