A novel metagenome-derived viral RNA polymerase and its application in a cell-free expression system for metagenome screening

A novel metagenome-derived viral RNA polymerase and its application in a cell-free expression system for metagenome screening

Abstract The mining of genomes from non-cultivated microorganisms using metagenomics is a powerful tool to discover novel proteins and other valuable biomolecules. However, function-based metagenome searches are often limited by the time-consuming expression of the active proteins in various heterol...

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Bibliographic Details
Main Authors: Yuchen Han, Birhanu M. Kinfu, Fabian Blombach, Gwenny Cackett, Hongli Zhang, Pablo Pérez-García, Ines Krohn, Jesper Salomon, Volkan Besirlioglu, Tayebeh Mirzaeigarakani, Ulrich Schwaneberg, Jennifer Chow, Finn Werner, Wolfgang R. Streit
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-22383-x

Internet

https://doi.org/10.1038/s41598-022-22383-x

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