Pausing methotrexate prevents impairment of Omicron BA.1 and BA.2 neutralisation after COVID-19 booster vaccination

Pausing methotrexate prevents impairment of Omicron BA.1 and BA.2 neutralisation after COVID-19 booster vaccination

Objective The level of neutralising capacity against Omicron BA.1 and BA.2 after third COVID-19 vaccination in patients on paused or continuous methotrexate (MTX) therapy is unclear.Methods In this observational cohort study, neutralising serum activity against SARS-CoV-2 wild-type (Wu01) and varian...

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Bibliographic Details
Main Authors: Robert Biesen, Florian Kurth, Jan Zernicke, Florian Klein, Jens Klotsche, Amanthi Nadira Arumahandi de Silva, Leonie Maria Frommert, Alexander ten Hagen, Elisa Habermann, Lutz Gieselmann, Pinkus Tober-Lau, Fredrik Nils Albach, Elvin Ahmadov, Leif Erik Sander
Format: Article
Language:English
Published: BMJ Publishing Group 2022-10-01
Series:RMD Open
Online Access:https://rmdopen.bmj.com/content/8/2/e002639.full

Internet

https://rmdopen.bmj.com/content/8/2/e002639.full

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