A Comprehensive Investigation of Interactions between Antipsychotic Drug Quetiapine and Human Serum Albumin Using Multi-Spectroscopic, Biochemical, and Molecular Modeling Approaches

A Comprehensive Investigation of Interactions between Antipsychotic Drug Quetiapine and Human Serum Albumin Using Multi-Spectroscopic, Biochemical, and Molecular Modeling Approaches

Quetiapine (QTP) is a short-acting atypical antipsychotic drug that treats schizophrenia or manic episodes of bipolar disorder. Human serum albumin (HSA) is an essential transport protein that transports hormones and various other ligands to their intended site of action. The interactions of QTP wit...

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Bibliographic Details
Main Authors: Seema Zargar, Tanveer A. Wani, Nawaf A. Alsaif, Arwa Ishaq A. Khayyat
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Molecules
Subjects:
quetiapine
human serum albumin
hydrophobic interaction
thermodynamic parameters
Online Access:https://www.mdpi.com/1420-3049/27/8/2589

Internet

https://www.mdpi.com/1420-3049/27/8/2589

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