Endothelial cells' activation and apoptosis induced by a subset of antibodies against human cytomegalovirus: relevance to the pathogenesis of atherosclerosis.

BACKGROUND:Human cytomegalovirus (hCMV) is involved in the pathogenesis of atherosclerosis. We have previously shown in patients with atherosclerosis that antibodies directed against the hCMV-derived proteins US28 and UL122 are able to induce endothelial cell damage and apoptosis of non-stressed end...

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Bibliographic Details
Main Authors: Claudio Lunardi, Marzia Dolcino, Dimitri Peterlana, Caterina Bason, Riccardo Navone, Nicola Tamassia, Elisa Tinazzi, Ruggero Beri, Roberto Corrocher, Antonio Puccetti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-05-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0000473