METTL16 promotes glycolytic metabolism reprogramming and colorectal cancer progression

METTL16 promotes glycolytic metabolism reprogramming and colorectal cancer progression

Abstract Background Glycolysis is the key hallmark of cancer and maintains malignant tumor initiation and progression. The role of N6-methyladenosine (m6A) modification in glycolysis is largely unknown. This study explored the biological function of m6A methyltransferase METTL16 in glycolytic metabo...

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Bibliographic Details
Main Authors: Wei Wei, Zhong-Yuan Zhang, Bin Shi, Yike Cai, Hou-Shun Zhang, Chun-Lei Sun, Yun-Fei Fei, Wen Zhong, Shuang Zhang, Chen Wang, Bing He, Guan-Min Jiang, Hao Wang
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Colorectal cancer
m6A
METTL16
SOGA1
PDK4
Online Access:https://doi.org/10.1186/s13046-023-02732-y

Internet

https://doi.org/10.1186/s13046-023-02732-y

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