Tandem mass tag-based quantitative proteomics analysis reveals the effects of the α-lactalbumin peptides GINY and DQW on lipid deposition and oxidative stress in HepG2 cells

Tandem mass tag-based quantitative proteomics analysis reveals the effects of the α-lactalbumin peptides GINY and DQW on lipid deposition and oxidative stress in HepG2 cells

ABSTRACT: The objective of this study was to investigate the mechanism by which the α-lactalbumin peptides Gly-Ile-Asn-Tyr (GINY) and Asp-Gln-Trp (DQW) ameliorate free fatty acid–induced lipid deposition in HepG2 cells. The results show that GINY and DQW reduced triglyceride, total cholesterol, and...

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Bibliographic Details
Main Authors: Haoran Chen, Xiaofen Qi, Kaifang Guan, Rongchun Wang, Qiming Li, Ying Ma
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Journal of Dairy Science
Subjects:
α-lactalbumin
GINY
DQW
proteomic
lipid deposition
Online Access:http://www.sciencedirect.com/science/article/pii/S0022030223000528

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http://www.sciencedirect.com/science/article/pii/S0022030223000528

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