Engineering extracellular vesicles with macrophage membrane fusion for ameliorating imiquimod-induced psoriatic skin inflammation

Engineering extracellular vesicles with macrophage membrane fusion for ameliorating imiquimod-induced psoriatic skin inflammation

Introduction Herein, we developed an engineered extracellular vehicle (EV)-based method for ameliorating inflammatory responses in psoriasis. Methods EVs, derived from annexin A1 (ANXA1) overexpressing T cells, were co-extruded with M2 macrophage membrane to obtain engineered EVs. In vitro, the effe...

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Bibliographic Details
Main Authors: Zeng Wang, Zhizhen Qin, Jiadie Wang, Xinqi Xu, Mengxin Zhang, Yuyue Liang, Yukun Huang, Zengyang Yu, Yu Gong, Luxian Zhou, Yiran Qiu, Minglu Ma, Dan Li, Bin Li
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Journal of Dermatological Treatment
Subjects:
engineered extracellular vesicles
psoriasis
annexin a1
macrophages
Online Access:http://dx.doi.org/10.1080/09546634.2023.2220445

Internet

http://dx.doi.org/10.1080/09546634.2023.2220445

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