Cadmium chloride down-regulates the expression of Rad51 in HC11 cells and reduces knock-in efficiency
Background: Efficient gene editing technology is needed for successful knock-in. Homologous recombination (HR) is a major double-strand break repair pathway that can be utilized for accurately inserting foreign genes into the genome. HR occurs during the S/G2 phase, and the DNA mismatch repair (MMR)...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
The Korean Society of Animal Reproduction and Biotechnology
2023-09-01
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| Series: | Journal of Animal Reproduction and Biotechnology |
| Subjects: | |
| Online Access: | https://www.e-jarb.org/journal/view.html?uid=2660&vmd=Full |