Initial biological evaluations of 18F-KS1, a novel ascorbate derivative to image oxidative stress in cancer

Initial biological evaluations of 18F-KS1, a novel ascorbate derivative to image oxidative stress in cancer

Abstract Background Reactive oxygen species (ROS)-induced oxidative stress damages many cellular components such as fatty acids, DNA, and proteins. This damage is implicated in many disease pathologies including cancer and neurodegenerative and cardiovascular diseases. Antioxidants like ascorbate (v...

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Bibliographic Details
Main Authors: Kiran Kumar Solingapuram Sai, Nagaraju Bashetti, Xiaofei Chen, Skylar Norman, Justin W. Hines, Omsai Meka, J. V. Shanmukha Kumar, Sriram Devanathan, Gagan Deep, Cristina M. Furdui, Akiva Mintz
Format: Article
Language:English
Published: SpringerOpen 2019-05-01
Series:EJNMMI Research
Subjects:
Positron emission tomography (PET)
Prostate cancer
Head and neck squamous cancer
Ascorbate
Biodistribution
Online Access:http://link.springer.com/article/10.1186/s13550-019-0513-x

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http://link.springer.com/article/10.1186/s13550-019-0513-x

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