Fetal Tissue-Derived Mast Cells (MC) as Experimental Surrogate for In Vivo Connective Tissue MC

Fetal Tissue-Derived Mast Cells (MC) as Experimental Surrogate for In Vivo Connective Tissue MC

Bone-marrow-derived mast cells are matured from bone marrow cells in medium containing 20% fetal calf serum (FCS), interleukin (IL)-3 and stem-cell factor (SCF) and are used as in vitro models to study mast cells (MC) and their role in health and disease. In vivo, however, BM-derived hematopoietic s...

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Bibliographic Details
Main Authors: Caterina Iuliano, Magdalena Absmaier-Kijak, Tobias Sinnberg, Nils Hoffard, Miriam Hils, Martin Köberle, Florian Wölbing, Ekaterina Shumilina, Nicole Heise, Birgit Fehrenbacher, Martin Schaller, Florian Lang, Susanne Kaesler, Tilo Biedermann
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cells
Subjects:
mast cell
in vitro model
transcriptome
RNA sequencing
proteases
IgE
Online Access:https://www.mdpi.com/2073-4409/11/6/928

Internet

https://www.mdpi.com/2073-4409/11/6/928

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