Engineering hypertrophic cartilage grafts from lipoaspirate for critical‐sized calvarial bone defect reconstruction: An adipose tissue‐based developmental engineering approach

Abstract Developmental engineering of living implants from different cell sources capable of stimulating bone regeneration by recapitulating endochondral ossification (ECO) is a promising strategy for large bone defect reconstruction. However, the clinical translation of these cell‐based approaches...

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Bibliographic Details
Main Authors: Ru‐Lin Huang, Rao Fu, Yuxin Yan, Chuanqi Liu, Jing Yang, Yun Xie, Qingfeng Li
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:Bioengineering & Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/btm2.10312