redPATH: Reconstructing the Pseudo Development Time of Cell Lineages in Single-cell RNA-seq Data and Applications in Cancer

redPATH: Reconstructing the Pseudo Development Time of Cell Lineages in Single-cell RNA-seq Data and Applications in Cancer

The recent advancement of single-cell RNA sequencing (scRNA-seq) technologies facilitates the study of cell lineages in developmental processes and cancer. In this study, we developed a computational method, called redPATH, to reconstruct the pseudo developmental time of cell lineages using a consen...

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Bibliographic Details
Main Authors: Kaikun Xie, Zehua Liu, Ning Chen, Ting Chen
Format: Article
Language:English
Published: Oxford University Press 2021-04-01
Series:Genomics, Proteomics & Bioinformatics
Subjects:
Single-cell pseudotime reconstruction
Consensus Hamiltonian path
Cell differentiation
Cell proliferation
Cell development and diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S167202292100019X

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http://www.sciencedirect.com/science/article/pii/S167202292100019X

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