A review of metabolic and enzymatic engineering strategies for designing and optimizing performance of microbial cell factories

A review of metabolic and enzymatic engineering strategies for designing and optimizing performance of microbial cell factories

Microbial cell factories (MCFs) are of considerable interest to convert low value renewable substrates to biofuels and high value chemicals. This review highlights the progress of computational models for the rational design of an MCF to produce a target bio-commodity. In particular, the rational de...

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Bibliographic Details
Main Authors: Amanda K. Fisher, Benjamin G. Freedman, David R. Bevan, Ryan S. Senger
Format: Article
Language:English
Published: Elsevier 2014-08-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Metabolic engineering
Enzyme engineering
Microbial cell factory
Genome-scale model
Docking
Molecular dynamics
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037014000257

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http://www.sciencedirect.com/science/article/pii/S2001037014000257

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