Stress-related exposures amplify the effects of genetic susceptibility on depression and anxiety
Abstract It is unclear whether and to what extent stress-related exposures moderate the effects of polygenic risk scores (PRSs) on depression and anxiety. We aimed to examine such moderation effects for a variety of stress-related exposures on depression and anxiety. We included 41,810 participants...
Main Authors: | Rujia Wang, Lifelines Cohort Study, Catharina A. Hartman, Harold Snieder |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-01-01
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Series: | Translational Psychiatry |
Online Access: | https://doi.org/10.1038/s41398-023-02327-3 |
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