Sphingosine-1-phosphate hinders the osteogenic differentiation of dental pulp stem cells in association with AKT signaling pathways

Abstract Sphingosine-1-phosphate (S1P) is an important lipid mediator that regulates a diverse range of intracellular cell signaling pathways that are relevant to tissue engineering and regenerative medicine. However, the precise function of S1P in dental pulp stem cells (DPSCs) and its osteogenic d...

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Bibliographic Details
Main Authors: Bongkun Choi, Ji-Eun Kim, Si-On Park, Eun-Young Kim, Soyoon Oh, Hyuksu Choi, Dohee Yoon, Hyo-Jin Min, Hyung-Ryong Kim, Eun-Ju Chang
Format: Article
Language:English
Published: Nature Publishing Group 2022-04-01
Series:International Journal of Oral Science
Online Access:https://doi.org/10.1038/s41368-022-00173-5