Metabolic Syndrome and Male Fertility
Metabolic syndrome (MetS) represents a cluster of conditions that have a negative impact on human health overall. Its preva-lence has been rapidly increasing worldwide and has coincided with a global decrease in birth rates and fertility potential. This review aims to address this observation throug...
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Format: | Article |
Language: | English |
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Korean Society for Sexual Medicine and Andrology
2019-05-01
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Series: | The World Journal of Men's Health |
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author | Ana Dias Martins Ahmad Majzoub Ashok Agawal |
author_facet | Ana Dias Martins Ahmad Majzoub Ashok Agawal |
author_sort | Ana Dias Martins |
collection | DOAJ |
description | Metabolic syndrome (MetS) represents a cluster of conditions that have a negative impact on human health overall. Its preva-lence has been rapidly increasing worldwide and has coincided with a global decrease in birth rates and fertility potential. This review aims to address this observation through studying the relationship between MetS and male reproductive health. The effects of obesity, dyslipidemia, hypertension, and insulin resistance on male fertility were examined and supporting evi-dence explaining the pathophysiology of sperm dysfunction with each MetS component were described. Adopting a healthy lifestyle appears to be the single most important intervention to prevent the unwanted effects of MetS on men’s health and fertility. Further studies addressing the components of MetS and their impact on male reproduction are required to enhance our understanding of the underlying pathophysiology and to propose new methods for therapeutic intervention. |
first_indexed | 2024-12-21T01:31:48Z |
format | Article |
id | doaj.art-84fddcfa33ce40a9bd99d19ac3572d07 |
institution | Directory Open Access Journal |
issn | 2287-4208 2287-4690 |
language | English |
last_indexed | 2024-12-21T01:31:48Z |
publishDate | 2019-05-01 |
publisher | Korean Society for Sexual Medicine and Andrology |
record_format | Article |
series | The World Journal of Men's Health |
spelling | doaj.art-84fddcfa33ce40a9bd99d19ac3572d072022-12-21T19:20:21ZengKorean Society for Sexual Medicine and AndrologyThe World Journal of Men's Health2287-42082287-46902019-05-0137211312710.5534/wjmh.180055Metabolic Syndrome and Male FertilityAna Dias Martins0Ahmad Majzoub1Ashok Agawal2American Center for Reproductive Medicine, Department of Urology, Cleveland Clinic, Cleveland, OH, USADepartment of Urology, Hamad Medical Corporation and Weill Cornell Medicine-Qatar, Doha, QatarAmerican Center for Reproductive Medicine, Department of Urology, Cleveland Clinic, Cleveland, OH, USAMetabolic syndrome (MetS) represents a cluster of conditions that have a negative impact on human health overall. Its preva-lence has been rapidly increasing worldwide and has coincided with a global decrease in birth rates and fertility potential. This review aims to address this observation through studying the relationship between MetS and male reproductive health. The effects of obesity, dyslipidemia, hypertension, and insulin resistance on male fertility were examined and supporting evi-dence explaining the pathophysiology of sperm dysfunction with each MetS component were described. Adopting a healthy lifestyle appears to be the single most important intervention to prevent the unwanted effects of MetS on men’s health and fertility. Further studies addressing the components of MetS and their impact on male reproduction are required to enhance our understanding of the underlying pathophysiology and to propose new methods for therapeutic intervention.DyslipidemiasGlucose intoleranceHypertensionmaleMetabolic syndromeObesitymale Infertility |
spellingShingle | Ana Dias Martins Ahmad Majzoub Ashok Agawal Metabolic Syndrome and Male Fertility The World Journal of Men's Health Dyslipidemias Glucose intolerance Hypertension male Metabolic syndrome Obesity male Infertility |
title | Metabolic Syndrome and Male Fertility |
title_full | Metabolic Syndrome and Male Fertility |
title_fullStr | Metabolic Syndrome and Male Fertility |
title_full_unstemmed | Metabolic Syndrome and Male Fertility |
title_short | Metabolic Syndrome and Male Fertility |
title_sort | metabolic syndrome and male fertility |
topic | Dyslipidemias Glucose intolerance Hypertension male Metabolic syndrome Obesity male Infertility |
work_keys_str_mv | AT anadiasmartins metabolicsyndromeandmalefertility AT ahmadmajzoub metabolicsyndromeandmalefertility AT ashokagawal metabolicsyndromeandmalefertility |