GWAS of Folate Metabolism With Gene–environment Interaction Analysis Revealed the Possible Role of Lifestyles in the Control of Blood Folate Metabolites in Japanese: The J-MICC Study

GWAS of Folate Metabolism With Gene–environment Interaction Analysis Revealed the Possible Role of Lifestyles in the Control of Blood Folate Metabolites in Japanese: The J-MICC Study

Background: The present genome-wide association study (GWAS) aimed to reveal the genetic loci associated with folate metabolites, as well as to detect related gene–environment interactions in Japanese. Methods: We conducted the GWAS of plasma homocysteine (Hcy), folic acid (FA), and vitamin B12 (VB1...

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Main Authors: Mineko Tsukamoto, Asahi Hishida, Takashi Tamura, Mako Nagayoshi, Rieko Okada, Yoko Kubo, Yasufumi Kato, Nobuyuki Hamajima, Yuichiro Nishida, Chisato Shimanoe, Rie Ibusuki, Kenichi Shibuya, Naoyuki Takashima, Yasuyuki Nakamura, Miho Kusakabe, Yohko Nakamura, Yuriko N. Koyanagi, Isao Oze, Takeshi Nishiyama, Sadao Suzuki, Isao Watanabe, Daisuke Matsui, Jun Otonari, Hiroaki Ikezaki, Sakurako Katsuura-Kamano, Kokichi Arisawa, Kiyonori Kuriki, Masahiro Nakatochi, Yukihide Momozawa, Kenji Takeuchi, Kenji Wakai, Keitaro Matsuo
Format: Article
Language:English
Published: Japan Epidemiological Association 2024-05-01
Series:Journal of Epidemiology
Subjects:
genome-wide association study
folate metabolism
gene–environment interaction
cardiovascular disease prevention
Online Access:https://www.jstage.jst.go.jp/article/jea/34/5/34_JE20220341/_pdf

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https://www.jstage.jst.go.jp/article/jea/34/5/34_JE20220341/_pdf

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