Early production of offspring by in vitro fertilization using first-wave spermatozoa from prepubertal male mice

Mature male mice (aged 10–12 weeks or older) are conventionally used for in vitro fertilization (IVF) in order to achieve high fertilization rates (e.g., > 70%). Here, we sought to determine the earliest age at which male mice (C57BL/6J strain) can be used efficiently for producing offspring...

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Bibliographic Details
Main Authors: Keiji MOCHIDA, Ayumi HASEGAWA, Narumi OGONUKI, Kimiko INOUE, Atsuo OGURA
Format: Article
Language:English
Published: The Society for Reproduction and Development 2019-08-01
Series:The Journal of Reproduction and Development
Subjects:
Online Access:https://www.jstage.jst.go.jp/article/jrd/65/5/65_2019-042/_pdf/-char/en