Cutting-edge advances in modeling the blood–brain barrier and tools for its reversible permeabilization for enhanced drug delivery into the brain

Cutting-edge advances in modeling the blood–brain barrier and tools for its reversible permeabilization for enhanced drug delivery into the brain

Abstract The blood–brain barrier (BBB) is a sophisticated structure whose full functionality is required for maintaining the executive functions of the central nervous system (CNS). Tight control of transport across the barrier means that most drugs, particularly large size, which includes powerful...

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Bibliographic Details
Main Authors: Amit Sharma, Diogo C. Fernandes, Rui L. Reis, Dominika Gołubczyk, Silke Neumann, Barbara Lukomska, Miroslaw Janowski, Marcin Kortylewski, Piotr Walczak, J. Miguel Oliveira, Jarek Maciaczyk
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Cell & Bioscience
Subjects:
Blood–brain barrier
Drug targets
In vitro models
In vivo models
Drug delivery
Organoid models
Online Access:https://doi.org/10.1186/s13578-023-01079-3

Internet

https://doi.org/10.1186/s13578-023-01079-3

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