Extracellular vesicles from virulent P. brasiliensis induce TLR4 and dectin-1 expression in innate cells and promote enhanced Th1/Th17 response

Extracellular vesicles from virulent P. brasiliensis induce TLR4 and dectin-1 expression in innate cells and promote enhanced Th1/Th17 response

ABSTRACTExtracellular vesicles (EVs) are membrane-enclosed nanoparticles that transport several biomolecules and are involved in important mechanisms and functions related to the pathophysiology of fungal diseases. EVs from Paracoccidioides brasiliensis, the main causative agent of Paracoccidioidomy...

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Bibliographic Details
Main Authors: Bruno Montanari Borges, Monique Gama de Santana, Nycolas Willian Preite, Valéria de Lima Kaminski, Gabriel Trentin, Fausto Almeida, Flávio Vieira Loures
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Virulence
Subjects:
Paracoccidioides brasiliensis
extracellular vesicles, proteome
granuloma
Paracoccidioidomycosis
dendritic cells
macrophages
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2024.2329573

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https://www.tandfonline.com/doi/10.1080/21505594.2024.2329573

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