BS Seeker: precise mapping for bisulfite sequencing

<p>Abstract</p> <p>Background</p> <p>Bisulfite sequencing using next generation sequencers yields genome-wide measurements of DNA methylation at single nucleotide resolution. Traditional aligners are not designed for mapping bisulfite-treated reads, where the unmethylat...

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Detalhes bibliográficos
Main Authors: Pellegrini Matteo, Cokus Shawn J, Chen Pao-Yang
Formato: Artigo
Idioma:English
Publicado em: BMC 2010-04-01
Colecção:BMC Bioinformatics
Acesso em linha:http://www.biomedcentral.com/1471-2105/11/203