In Vitro and In Vivo Drug-Response Profiling Using Patient-Derived High-Grade Glioma

In Vitro and In Vivo Drug-Response Profiling Using Patient-Derived High-Grade Glioma

Background: Genomic profiling cannot solely predict the complexity of how tumor cells behave in their in vivo microenvironment and their susceptibility to therapies. The aim of the study was to establish a functional drug prediction model utilizing patient-derived GBM tumor samples for in vitro test...

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Bibliographic Details
Main Authors: Robin G. Rajan, Virneliz Fernandez-Vega, Jantzen Sperry, Jonathan Nakashima, Long H. Do, Warren Andrews, Simina Boca, Rezwanul Islam, Sajeel A. Chowdhary, Jan Seldin, Glauco R. Souza, Louis Scampavia, Khalid A. Hanafy, Frank D. Vrionis, Timothy P. Spicer
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Cancers
Subjects:
organoid
GBM
cancer
phenotypic
high-throughput screening (HTS)
Online Access:https://www.mdpi.com/2072-6694/15/13/3289

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https://www.mdpi.com/2072-6694/15/13/3289

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