Lung Dendritic Cells Facilitate Extrapulmonary Bacterial Dissemination during Pneumococcal Pneumonia

Streptococcus pneumoniae is a leading cause of bacterial pneumonia worldwide. Given the critical role of dendritic cells (DCs) in regulating and modulating the immune response to pathogens, we investigated here the role of DCs in S. pneumoniae lung infections. Using a well-established transgenic mou...

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Bibliographic Details
Main Authors: Alva eRosendahl, Simone eBergmann, Sven eHammerschmidt, Oliver eGoldmann, Eva eMedina
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2013.00021/full