Exosomal RNF157 mRNA from prostate cancer cells contributes to M2 macrophage polarization through destabilizing HDAC1

Exosomal RNF157 mRNA from prostate cancer cells contributes to M2 macrophage polarization through destabilizing HDAC1

BackgroundExosomes have been identified to mediate the transmission of RNAs among different cells in tumor microenvironment, thus affecting the progression of different diseases. However, exosomal messenger RNAs (mRNAs) have been rarely explored. RNF157 mRNA has been found to be up-regulated in PCa...

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Bibliographic Details
Main Authors: Han Guan, Likai Mao, Jinfeng Wang, Sheng Wang, Shuai Yang, Hongliang Wu, Wenyan Sun, Zhijun Chen, Ming Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Oncology
Subjects:
exosomal RNF157 mRNA
prostate cancer
M2 macrophage polarization
HDAC1
ubiquitination
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1021270/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.1021270/full

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